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Invitrogen™ IRF4 Polyclonal Antibody
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Catalog No. PIPA582031
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100 μL
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PIPA582031 100 μL
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Catalog No. PIPA582031 Supplier Invitrogen™ Supplier No. PA582031
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ALAFSDCRLH ICLYYREILV KELTTSSPEG CRISHGHTYD ASNLDQVLFP YPEDNGQRKN IEKLLSHLER GVVLWMAPDG LYAKRLCQSR IYWDGPLALC NDRPNKLERD QTCKLFDTQQ FLSELQAFAH HGRSLPRFQV TLC Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 93%.

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRF4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IRF4
Gene Accession No. Q15306
Gene Alias AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP
Gene Symbols IRF4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IRF4. Recombinant protein control fragment (Product #RP-101901).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3662
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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