IRF7 Rabbit anti-Human, Clone: 2A1, Bioss

Catalog No.	Quantity
50-198-9588	100 μL

Catalog No. 50-198-9588 Supplier Bioss Supplier No. BSM52120R

Description

Rabbit Monoclonal Antibody

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.

Specifications

• Antigen: IRF7
• Applications: Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 2A1
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene: IRF7
• Gene Accession No.: Q92985
• Gene Alias: IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; IRF7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H
• Gene Symbols: IRF7
• Host Species: Rabbit
• Immunogen: Recombinant human IRF7 protein, around 200-300aa.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3665
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG