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IRF8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
$518.60
Specifications
| Antigen | IRF8 |
|---|---|
| Concentration | 1.11 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-173-2300
|
Proteintech Group Inc
189771AP150UL |
150 μL |
Each of 1 for $518.60
|
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Description
IRF8 (interferon regulatory factor 8) is a transcriptional activator or repressor. It specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes. IRF8 plays a negative regulatory role in cells of the immune system. It is involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells. This leads to recognition of AICE sequence, an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of the genes. Mutations in the gene can result in immunodeficiencey 32A and 32B.Specifications
| IRF8 | |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human, Mouse, Rat | |
| P23611, Q02556 | |
| 15900, 292060, 3394 | |
| Peptide | |
| Primary | |
| -20°C | |
| IRF8 |
| 1.11 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| H ICSBP, ICSBP, ICSBP1, interferon regulatory factor 8, IRF 8, IRF8 | |
| IRF8 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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