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Invitrogen™ IRG1 Polyclonal Antibody
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Catalog No. PIPA5102893
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Quantity:
100 μL
Catalog No. Quantity
PIPA5102893 100 μL
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Catalog No. PIPA5102893

Supplier: Invitrogen™ PA5102893

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IRG1.

Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)- mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; IRG1- mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRG1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ACOD1
Gene Accession No. A6NK06
Gene Alias ACOD1; Aconitate decarboxylase; aconitate decarboxylase 1; CAD; Cis-aconitate decarboxylase; cis-aconitic acid decarboxylase; Immune-responsive gene 1 protein; immune-responsive gene 1 protein homolog; immunoresponsive 1 homolog; IRG1
Gene Symbols ACOD1
Host Species Rabbit
Immunogen A synthesized peptide derived from human ACOD1(Accession A6NK06), corresponding to amino acid residues I439-S481.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 730249
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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