Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. FEPA5144875

Invitrogen™ IRG1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. FEPA5144875
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
FEPA5144875 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. FEPA5144875 Supplier Invitrogen™ Supplier No. PA5144875
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LGLSSTKCRE ALAIAVSHAG APMANAATQT KPLHIGNAAK HGIEAAFLAM LGLQGNKQVL DLEAGFGAFY ANYSPKVLPS IASYSWLLDQ Antigen sequence identity: Mouse 86%; Rat 87%.

Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)- mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; IRG1- mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRG1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ACOD1
Gene Accession No. A6NK06
Gene Alias ACOD1; Aconitate decarboxylase; aconitate decarboxylase 1; CAD; Cis-aconitate decarboxylase; cis-aconitic acid decarboxylase; Immune-responsive gene 1 protein; immune-responsive gene 1 protein homolog; immunoresponsive 1 homolog; IRG1
Gene Symbols ACOD1
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 177-266. Recombinant protein control fragment (Product #RP-109751).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 730249
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.