Invitrogen™ IRG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102893

Catalog No. PIPA5102893

Description

Antibody detects endogenous levels of total IRG1.

Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)- mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; IRG1- mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Specifications

• Antigen: IRG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACOD1
• Gene Alias: ACOD1; Aconitate decarboxylase; aconitate decarboxylase 1; CAD; Cis-aconitate decarboxylase; cis-aconitic acid decarboxylase; Immune-responsive gene 1 protein; immune-responsive gene 1 protein homolog; immunoresponsive 1 homolog; IRG1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 730249
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: A6NK06
• Gene Symbols: ACOD1
• Immunogen: A synthesized peptide derived from human ACOD1(Accession A6NK06), corresponding to amino acid residues I439-S481.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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