Invitrogen™ IRS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517056

Catalog No. PIPA517056

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with IRS-1.

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Specifications

• Antigen: IRS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IRS2
• Gene Alias: 4PS; insulin receptor substrate 2; Irs2; IRS-2; tyrosine kinase substrate
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29376, 384783, 8660
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 255 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: P81122, Q9Y4H2
• Gene Symbols: IRS2
• Immunogen: Synthetic peptide corresponding to residues surrounding Leu1326 of human IRS-2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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