Invitrogen™ IRS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121820

Catalog No. PIPA5121820

Description

IRS2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

Specifications

• Antigen: IRS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IRS2
• Gene Alias: 4PS; insulin receptor substrate 2; Irs2; IRS-2; tyrosine kinase substrate
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8660
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q9Y4H2
• Gene Symbols: IRS2
• Immunogen: Recombinant protein Insulin Receptor Substrate 2. The antigen corresponds to amino acid range 985-1255 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG