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IRSp53 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 110872AP150UL

Description
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal domit neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Specifications
IRSp53 | |
Polyclonal | |
Unconjugated | |
BAIAP2 | |
BAI associated protein 2, BAI1 associated protein 2, BAIAP2, BAP2, Fas ligand associated factor 3, FLAF3, Insulin receptor substrate p53, IRS 58, IRSp53, IRSp53/58, Protein BAP2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
10458, 108100, 117542 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.4 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q6GMN2, Q8BKX1, Q9UQB8 | |
BAIAP2 | |
IRSp53 Fusion Protein Ag1552 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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