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Invitrogen™ ISL1 Polyclonal Antibody
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Catalog No. PIPA5121000
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100 μL
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PIPA5121000 100 μL
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Catalog No. PIPA5121000 Supplier Invitrogen™ Supplier No. PA5121000
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, SH-SY5Y, Mouse thymus, Rat thymus. The target is usually found in the following locations: Nucleus. Immunogen sequence: MGDMGDPPKK KRLISLCVGC GNQIHDQYIL RVSPDLEWHA ACLKCAECNQ YLDESCTCFV RDGKTYCKRD YIRLYGIKCA KCSIGFSKND FVMRARSKVY HIECFRCVAC SRQLIPGDEF ALREDGLFCR ADHDVVERAS LGAGDPLSPL HPARPLQMAA EPISARQPAL RPHVHKQPEK TTRVRTVLNE KQLHTLRTCY AANPRPDALM KEQLVEMTGL SPRVIRVWFQ NKRCKDKKRS IMMKQLQQQQ PNDKTNIQGM TGTPMVAASP ERHDGGLQAN PVEVQSYQPP WKVLSDFALQ SDIDQPAFQQ LVNFSEGGPG SNSTGSEVAS MSSQLPDTPN SMVASPIEA.

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ISL1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ISL1
Gene Accession No. P61371, P61372, P61374
Gene Alias Insulin gene enhancer protein ISL-1; insulin related protein; ISL LIM homeobox 1; Isl1; Isl-1; isl-1 homeobox; ISL1 transcription factor LIM/homeodomain (islet-1); ISL1 transcription factor, LIM/homeodomain; ISL1 transcription factor, LIM/homeodomain 1; isl-1=homeobox; Islet 1; ISLET1; islet-1; Lim-homeodomain protein Islet1
Gene Symbols ISL1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human Islet1 (NP_0021932).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16392, 3670, 64444
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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