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Tocris Bioscience™ ISO 1
GREENER_CHOICE

Catalog No. 428810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Macrophage migration inhibitory factor (MIF) inhibitor

ISO 1 is a macrophage migration inhibitory factor (MIF) inhibitor (IC50 = 7 μM); inhibits MIF tautomerase activity in vitro and in vivo. Protective against mouse models of streptozotocin -induced diabetes mellitus; blocks anti-inflammatory response following LPS exposure and increases survival. Inhibits airway remodeling in a mouse model of chronic asthma. Cell permeable; orally bioavailable.

Chemical Identifiers

CAS 478336-92-4
Molecular Formula C12H13NO4

Specifications

Quantity 10 mg
Formula Weight 235.24
Physical Form Solid
Color White
Purity >98%
Molecular Weight (g/mol) 235.239
Chemical Name or Material ISO 1

Safety and Handling

Recommended Storage Store at +4°C
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