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Alfa Aesar™ Isopropylidene malonate, 98%

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Quantity:
25g
100g
500g
2033-24-1
C6H8O4
144.126
MFCD00006638
GXHFUVWIGNLZSC-UHFFFAOYSA-N
meldrum's acid,isopropylidene malonate,meldrums acid,1,3-dioxane-4,6-dione, 2,2-dimethyl,sub-isopropyl malonate,2,2-dimethyl-1,3-dioxan-4,6-dione,cycl-isopropylidene malonate,cyclic isopropylidene malonate,malonic acid cyclic isopropylidene ester,meldrum acid
16249
2,2-dimethyl-1,3-dioxane-4,6-dione
CC1(OC(=O)CC(=O)O1)C
2033-24-1
C6H8O4
144.126
MFCD00006638
GXHFUVWIGNLZSC-UHFFFAOYSA-N
meldrum's acid,isopropylidene malonate,meldrums acid,1,3-dioxane-4,6-dione, 2,2-dimethyl,sub-isopropyl malonate,2,2-dimethyl-1,3-dioxan-4,6-dione,cycl-isopropylidene malonate,cyclic isopropylidene malonate,malonic acid cyclic isopropylidene ester,meldrum acid
16249
2,2-dimethyl-1,3-dioxane-4,6-dione
CC1(OC(=O)CC(=O)O1)C
Applications
Isopropylidene malonate is an important reagent in synthetic chemistry and involved in the formation of new C-C bonds, rings, amides, esters, and acids. The presence of carbonyl groups at C-4 and C-6 positions favors the alkylation and acylation reactions due to its acidic nature. It is also employed as an antimicrobial agent. It is used in the preparation of 4-pyridyl-substituted heterocycles, 2-substituted indoles, isofraxidin and macrocyclic beta-keto lactones. Further, it is involved in the Knoevenagel condensation reaction with aldehydes.

Solubility
Soluble in water. Slightly soluble in ethanol and chloroform.

Notes
Store in a cool place. Incompatible with strong oxidizing agents.
Sensitivity Moisture sensitive
Melting Point 92°C to 96°C
Quantity 100g
Beilstein 117310
Merck Index 14,5817
Solubility Information Soluble in water. Slightly soluble in ethanol and chloroform.
Formula Weight 144.13
Percent Purity 98%
Chemical Name or Material Isopropylidene malonate

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362

H315

DOTInformation : Hazard Class: 9; Packaging Group: III

EINECSNumber : 217-992-8

RTECSNumber : JH0800000

TSCA : Yes

Recommended Storage : Ambient temperatures