Isradipine, 98+%, PROMO, Thermo Scientific Chemicals

Description

L-type calcium channel blocker

Applications

Isradipine is a L-type calcium channel blocker, Isradipine has anti-atherosclerotic effects in animals and improves endothelium-mediated nitric oxide (NO)-dependent vasodilation in vitro. Additional studies indicate that Isradipine may provide a neuroprotective effect in a rat model of focal ischemia and that Isradipine produces a dose-dependent sparing of dopamine neuronal fibers and cell bodies.

Solubility

Soluble in DMSO

Notes

Protect from heat. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 75695-93-1
• Molecular Formula: C19H21N3O5
• Molecular Weight (g/mol): 371.39 g/mol
• MDL Number: MFCD00153820
• InChI Key: HMJIYCCIJYRONP-UHFFFAOYNA-N
• Synonym: isradipine, dynacirc, isradipin, lomir, isrodipine, prescal, dynacirc cr, esradin, clivoten, dynacrine
• PubChem CID: 3784
• IUPAC Name: 3-methyl 5-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• SMILES: COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C

• Color: Yellow
• Quantity: 50 mg
• Merck Index: 14,5240
• Solubility Information: Soluble in DMSO
• Percent Purity: ≥98%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Isradipine

Safety and Handling

TSCA	No
Recommended Storage	Keep cold

RUO - Research Use Only