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Invitrogen™ IST1 Polyclonal Antibody
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Catalog No. PIPA597212
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100 μL
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PIPA597212 100 μL
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Catalog No. PIPA597212 Supplier Invitrogen™ Supplier No. PA597212
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MLGSGFKAER LRVNLRLVIN RLKLLEKKKT ELAQKARKEI ADYLAAGKDE RARIRVEHII REDYLVEAME ILELYCDLLL ARFGLIQSMK ELDSGLAESV STLIWAAPRL QSEVAELKIV ADQLCAKYSK EYGKLCRTNQ IGTVNDRLMH KLSVEAPPKI LVERYLIEIA KNYNVPYEPD SVVMAEAPPG VETDLIDVGF TDDVKKGGPG RGGSGGFTAP VGGPDGTVPM PMPMPMPMPS ANTPFSYPLP KGPVDDINAD KNISSAQIVG PGPKPEASAK LPSRPADNYD NFVLPELPSV PDTLPTASAG ASTSASEDID FDDLSRRFEE LKKKT; Positive Samples: A-549, HeLa, Mouse heart, Rat brain; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Midbody, centrosome, cytoskeleton, microtubule organizing center.

Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IST1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene IST1
Gene Accession No. P53990, Q568Z6, Q9CX00
Gene Alias 2400003C14Rik; AW536298; fb16b04; hIST1; hypothetical protein LOC321460; hypothetical protein LOC508900; increased sodium tolerance 1 homolog; increased sodium tolerance 1 homolog (yeast); IST1; IST1 factor associated with ESCRT-III; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; IST1, ESCRT-III associated factor; IST1-like protein; Kiaa0174; KIAA0174-like protein; MAPK activating protein PM28; MGC117220; mKIAA0174; OLC1; overexpressed in lung cancer 1; pm28; putative MAPK-activating protein PM28; RGD1307799; wu:fb16b04; wu:fi89e07; zgc:55671
Gene Symbols IST1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human IST1 (NP_0012579061).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 307833, 71955, 9798
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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