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  8. ISX 9, Tocris Bioscience™

ISX 9, Tocris Bioscience™
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Catalog No. 443950
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation

ISX 9 is a neurogenic agent. Mediates neuroD reporter gene induction via activation of Ca2+ influx; increases expression of neurogenic differentiation 1 (NeuroD1) transcription factor. Induces neuronal differentiation in human cortical neuronal cells (HCN), adult mouse whole brain (MWB) and subventricular zone (SVZ) progenitors. Also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro.

ISX 9 synthesized to Ancillary Material Grade also available.

For more information about how ISX 9 may be used, see our protocol: Transdifferentiating Fibroblasts into Neurons .

Chemical Identifiers

CAS 832115-62-5
Molecular Formula C11H10N2O2S
Molecular Weight (g/mol) 234.273
InChI Key SYENTKHGMVKGAQ-UHFFFAOYSA-N
PubChem CID 19582717
IUPAC Name N-cyclopropyl-5-thiophen-2-yl-1,2-oxazole-3-carboxamide
SMILES C1CC1NC(=O)C2=NOC(=C2)C3=CC=CS3

Specifications

Quantity 50 mg
Synonym isx-9, isx 9, n-cyclopropyl-5-thiophen-2-yl isoxazole-3-carboxamide, isoxazole 9 isx-9, neuronal differentiation inducer iii, n-cyclopropyl-5-thiophen-2-yl-1,2-oxazole-3-carboxamide, isoxazole 9, isx9, isoxazole 9 isx9, n-cyclopropyl-5-2-thienyl-3-isoxazolecarboxamide
Formula Weight 234.27
Percent Purity >99%
Chemical Name or Material ISX 9

Safety and Handling

Recommended Storage Store at +4°C
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