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ISX 9, Tocris Bioscience™

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Quantity:
10 mg
50 mg
Description
ISX 9 is a neurogenic agent. Mediates neuroD reporter gene induction via activation of Ca2+ influx; increases expression of neurogenic differentiation 1 (NeuroD1) transcription factor. Induces neuronal differentiation in human cortical neuronal cells (HCN), adult mouse whole brain (MWB) and subventricular zone (SVZ) progenitors. Also shown to induce cardiomyogenic differentiation of Notch-activated epicardium-derived cells in vitro.
ISX 9 synthesized to Ancillary Material Grade also available.
For more information about how ISX 9 may be used, see our protocol: Transdifferentiating Fibroblasts into Neurons .
Specifications
Specifications
Quantity | 50 mg |
Synonym | isx-9, isx 9, n-cyclopropyl-5-thiophen-2-yl isoxazole-3-carboxamide, isoxazole 9 isx-9, neuronal differentiation inducer iii, n-cyclopropyl-5-thiophen-2-yl-1,2-oxazole-3-carboxamide, isoxazole 9, isx9, isoxazole 9 isx9, n-cyclopropyl-5-2-thienyl-3-isoxazolecarboxamide |
Formula Weight | 234.27 |
Percent Purity | >99% |
Chemical Name or Material | ISX 9 |
Safety and Handling
Recommended Storage | Store at +4°C |
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