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IT1t dihydrochloride, Tocris Bioscience™
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Catalog No. 459650
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent CXCR4 antagonist

Potent CXCR4 antagonist (IC50 = 1.1 nM in calcium mobilization assays). Orally available. Blocks interaction with the HIV envelope protein, gp120 (IC50 = 7 nM, inhibition of X4-tropic HIV-1IIIB attachment).

Chemical Identifiers

CAS 1092776-63-0
Molecular Formula C21H36Cl2N4S2
Molecular Weight (g/mol) 479.567
InChI Key HFXJOXOIINQOEB-UHFFFAOYSA-N
Synonym it1t dihydrochloride, z-n,n'-dicyclohexyl 6,6-dimethyl-5h-imidazo 2,1-b 1,3 thiazol-3-yl methyl sulfanylmethanimidamide dihydrochloride, n,n'-dicyclohexylcarbamimidothioic acid 5,6-dihydro-6,6-dimethylimidazo 2,1-b thiazol-3-yl methyl ester dihydrochloride
PubChem CID 25178351
IUPAC Name (6,6-dimethyl-5H-imidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylcarbamimidothioate;dihydrochloride
SMILES CC1(CN2C(=CSC2=N1)CSC(=NC3CCCCC3)NC4CCCCC4)C.Cl.Cl

Specifications

Quantity 50 mg
Formula Weight 479.57
Percent Purity >99%
Chemical Name or Material IT1t dihydrochloride

Safety and Handling

Recommended Storage Store at +4°C
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