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Invitrogen™ ITFG2 Polyclonal Antibody
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Catalog No. PIPA5103447
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100 μL
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PIPA5103447 100 μL
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Catalog No. PIPA5103447 Supplier Invitrogen™ Supplier No. PA5103447
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ITFG2.

As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITFG2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ITFG2
Gene Accession No. Q91WI7, Q969R8
Gene Alias 2700050P07Rik; AI646725; integrin alpha FG-GAP repeat containing 2; integrin-alpha FG-GAP repeat-containing protein 2; integrin-alpha FG-GAP repeat-containing protein 2; KICSTOR complex protein ITFG2; ITFG2; KICSTOR complex protein ITFG2; MDS028; RGD1311944
Gene Symbols ITFG2
Host Species Rabbit
Immunogen A synthesized peptide derived from human ITFG2(Accession Q969R8), corresponding to amino acid residues L198-R248.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101142, 55846
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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