Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ ITGA4 Monoclonal Antibody (5C4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517102

Catalog No. PIMA517102


Only null left
Add to Cart

Description

Description

MA5-17102 targets ITGA4 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17102 immunogen is purified recombinant fragment of human ITGA4 expressed in E. Coli. MA5-17102 detects ITGA4 which has a predicted molecular weight of approximately 115kDa.

The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ITGA4
Monoclonal
1 mg/mL
PBS with 0.05% sodium azide
P13612
ITGA4
Purified recombinant fragment of human ITGA4 expressed in E. Coli.
100 μg
Primary
Human
Antibody
IgG1
ELISA, Flow Cytometry, Western Blot
5C4
Unconjugated
ITGA4
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha
Mouse
Protein G
RUO
3676
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.