Invitrogen™ ITGA5/CD61 Monoclonal Antibody (BV3)

Catalog No.	Quantity
PIMA533346	100 μg

Catalog No. PIMA533346 Supplier Invitrogen™ Supplier No. MA533346

Description

Mouse Monoclonal Antibody

Product is supplied at 1 mL (100 μL/mL). Application Notes: Flow cytometry - This antibody stains the extracellular domain of integrin ITGA5/CD61 . The cells were fixed in 4% paraformaldehyde before before analysis. IHC- Tussue sections fixed in Histochoice and blocked with 5% BSA. Positive control: HUVEC cells.

Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells.

Specifications

• Antigen: ITGA5/CD61
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry
• Classification: Monoclonal
• Clone: BV3
• Concentration: 100 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene: ITCH
• Gene Accession No.: Q96J02
• Gene Alias: 6720481N21Rik; 8030492O04Rik; A130065M08; ADMFD; AIF4; AIP4; atrophin-1 interacting protein 4; Atrophin-1-interacting protein 4; C230047C07Rik; dJ468O1.1; E3 ubiquitin-protein ligase Itchy; E3 ubiquitin-protein ligase Itchy homolog; HECT-type E3 ubiquitin transferase Itchy homolog; ITCH; itch E3 ubiquitin ligase; itchy E3 ubiquitin protein ligase; itchy E3 ubiquitin protein ligase homolog; itchy, E3 ubiquitin protein ligase; NAPP1; NFE2-associated polypeptide 1
• Gene Symbols: ITCH
• Host Species: Mouse
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 311567, 419145, 83737
• Target Species: Human, Rat, Chicken
• Content And Storage: 4°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1