Invitrogen™ ITGA7 Monoclonal Antibody (334908)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA524065

Catalog No. PIMA524065

Description

Reactivity with other Integrin alpha 7 isoforms was not tested. In direct ELISAs, no cross-reactivity with recombinant mouse Integrin alpha 2, alpha 3, alpha 4, alpha 5, alpha 9, alpha E, alpha X, recombinant human Integrin alpha L, or alpha 11 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.

Specifications

• Antigen: ITGA7
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q61738
• Gene Symbols: Itga7
• Immunogen: CHO-derived recombinant mouse Integrin alpha 7 Phe34-Pro1036.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry
• Clone: 334908
• Conjugate: Unconjugated
• Gene: Itga7
• Gene Alias: [a]7; alpha 7A integrin; alpha7; H36-alpha7; integrin alpha 7; integrin alpha 7 chain; integrin alpha-7; Integrin alpha-7 70 kDa form; Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; integrin subunit alpha 7; integrin, alpha 7; ITGA7; UNQ406/PRO768
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 16404
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized