Invitrogen™ ITGA7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589699

Catalog No. PIPA589699

Description

Immunogen sequence: QVELEGGQGP GQKGLCSPRP NILHLDVDSR DRRRRELEPP EQQEPGERQE PSMSWWPVSS AEKKKNITLD CARGTANCVV FSCPLYSFDR AAVLHVWGRL WNSTFLEEYS AVKSLEVIVR ANITVKSSIK NLMLRDASTV I; Positive Samples: U-87MG; Cellular Location: Membrane, Single-pass type I membrane protein.

Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.

Specifications

• Antigen: ITGA7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Itga7
• Gene Alias: [a]7; alpha 7A integrin; alpha7; H36-alpha7; integrin alpha 7; integrin alpha 7 chain; integrin alpha-7; Integrin alpha-7 70 kDa form; Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; integrin subunit alpha 7; integrin, alpha 7; ITGA7; UNQ406/PRO768
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3679
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q13683
• Gene Symbols: Itga7
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 880-1020 of human ITGA7 (NP_0021972).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov