ITGAL Mouse anti-Human, PE, Clone: 4A122, Abnova™
Mouse monoclonal antibody raised against human ITGAL.
Manufacturer: Abnova Corporation MAB12386
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
|Mouse monoclonal antibody raised against human ITGAL.|
|In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)|
|Store at 4°C. Do not freeze.|
|Flow Cytometry, Immunofluorescence|
|Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.|
|Protein A/G affinity chromatography|
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