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ITGAM Mouse anti-Human, PE, Clone: 4AM216, Abnova™

Catalog No. 89934391 Shop All Abnova Corporation Products
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Catalog No. 89-934-391 Supplier Abnova Corporation Supplier No. MAB12388
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Description

Mouse monoclonal antibody raised against human ITGAM.

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen ITGAM
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone 4AM216
Conjugate PE
Description Mouse monoclonal antibody raised against human ITGAM.
Dilution Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
Gene Alias CD11B/CR3A/MAC-1/MAC1A/MGC117044/MO1A/SLEB6
Gene Symbols ITGAM
Host Species Mouse
Immunogen ITGAM
Purification Method Protein A/G affinity chromatography
Quantity 50 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3684
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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