ITGAM Rabbit anti-Human, Clone:RM290, Abnova™

Catalog No.	Quantity
89-333-267	100 μL

Catalog No. 89-333-267 Supplier Abnova Corporation Supplier No. MAB16920

Description

Rabbit monoclonal antibody raised against human ITGAM.

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (′Mac-1′), or inactivated-C3b (iC3b) receptor 3 (′CR3′). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: ITGAM
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: RM290
• Conjugate: Unconjugated
• Description: integrin, alpha M (complement component 3 receptor 3 subunit)
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-200)
  Western Blot (1:200-500)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
• Gene: ITGAM
• Gene Alias: CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6
• Host Species: Rabbit
• Immunogen: A peptide corresponding to C-terminus of human ITGAM.
• Quantity: 100 μL
• Gene ID (Entrez): 3684
• Test Specificity: This antibody reacts to human CD11b (Integrin alpha-M).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG