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Invitrogen™ ITGB5 Polyclonal Antibody
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Catalog No. PIPA517260
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100 μL
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PIPA517260 100 μL
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Catalog No. PIPA517260 Supplier Invitrogen™ Supplier No. PA517260
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell-surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in-groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N-terminal extracellular domain that binds the ECM ligand and a small C-terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITGB5
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 60 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene Itgb5
Gene Accession No. P18084
Gene Alias [b]5; [b]-5; [b]5A; [b]5B; AA475909; AI874634; beta5; beta-5; CD61; ESTM23; FLJ26658; GP3A; GPIIIa; I79_000655; integrin beta 5; integrin beta-5; integrin subunit beta 5; integrin, beta 5; ITGB5; RGD1563276; testis secretory sperm-binding protein Li 217p
Gene Symbols Itgb5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding Lys789 of human integrin β5 protein.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3693
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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