ITIH4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-4230	Proteintech Group Inc 240691AP150UL	150 μL

Description

The inter-alpha-trypsin inhibitor (ITI, I-alpha-I) family is a classic example of protein-glycosaminoglycoprotein (PGP) complexes. They occur constitutively in plasma at relatively high concentrations and results from alternating combinations of three kinds of heavy chains with a common light chain called the bikunin proteoglycan. Bikunin has two proteinase inhibitor domains and belongs to the Kunitz-type protease inhibitor family; it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.

Specifications

• Antigen: ITIH4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: A6X935, Q14624
• Gene ID (Entrez): 16427, 3700
• Immunogen: ITIH4 Fusion Protein Ag21275
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ITIH4

• Concentration: 0.35 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Gp120, H4P, IHRP, ITI HC4, ITI heavy chain H4, ITIH4, ITIHL1, PK 120, PK120
• Gene Symbols: Itih4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody