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Invitrogen™ ITM2C Polyclonal Antibody
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Catalog No. PIPA5116254
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400 μL
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Catalog No. Quantity
PIPA5116254 400 μL
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Catalog No. PIPA5116254 Supplier Invitrogen™ Supplier No. PA5116254
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Description

Rabbit Polyclonal Antibody

ITM2C Polyclonal Antibody for Western Blot

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITM2C
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene ITM2C
Gene Accession No. Q9NQX7
Gene Alias 3110038L02Rik; BRI3; Bricd2c; BRICHOS domain containing 2C; cerebral protein 14; CT-BRI3; E25; E25C; hRPC.1050_D_4; hucep-14; Integral membrane protein 2C; integral membrane protein 3; Itm2c; ITM3; NPD018; PSEC0047; Transmembrane protein BRI3
Gene Symbols ITM2C
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81618
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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