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ITM2C Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981727
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Catalog No. Quantity
50-198-1727 100 μL
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Catalog No. 50-198-1727 Supplier Bioss Supplier No. BS11859R
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Description

Rabbit Polyclonal Antibody

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

Specifications

Antigen ITM2C
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ITM2C
Gene Accession No. Q9NQX7
Gene Alias BRI3; BRICD2C; BRICHOS domain containing 2C; Cerebral protein 14; CT-BRI3; E25; E25C; hRPC.1050_D_4; hucep-14; Integral membrane protein 2C; integral membrane protein 3; ITM2C; ITM3; NPD018; PSEC0047; Transmembrane protein BRI3
Gene Symbols ITM2C
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ITM2C.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81618
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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