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ITM2C Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 136011AP150UL

Encompass_Preferred

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Catalog No. 50-172-8866


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Description

Description

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
Specifications

Specifications

ITM2C
Polyclonal
Unconjugated
ITM2C
BRI3, BRICD2C, Cerebral protein 14, E25, E25C, integral membrane protein 2C, ITM2C, ITM3, PSEC0047, Transmembrane protein BRI3
Rabbit
Antigen Affinity Chromatography
RUO
81618
-20°C
Liquid
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.19 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9NQX7
ITM2C
ITM2C Fusion Protein Ag3876
150 μL
Primary
Human
Antibody
IgG
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