Invitrogen™ ITPKA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559185

Catalog No. PIPA559185

Description

Immunogen sequence: DGSCSTDFKT TRSREQVLRV FEEFVQGDEE VLRRYLNRLQ QIRDTLEVSE FFRRHEV Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 89%.

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

Specifications

• Antigen: ITPKA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ITPKA
• Gene Alias: EC 2.7.1.127; inositol 1,4,5-triphosphate 3-kinase; inositol 1,4,5-trisphosphate 3-kinase A; inositol 145-triphosphate 3-kinase; inositol-trisphosphate 3-kinase A; insP 3-kinase A; IP3 3 kinase A; IP3 3-kinase A; IP3-3KA; IP3K A; IP3KA; IP3-kinase A; ITPKA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3706
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P23677
• Gene Symbols: ITPKA
• Immunogen: Recombinant protein corresponding to Human ITPKA. Recombinant protein control fragment (Product #RP-98080).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov