ITPKA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA585786

Catalog No. PIPA585786

Description

Keep as concentrated solution. Predicted reactivity: Mouse (100%). Positive Control: mouse brain, rat brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.

Specifications

• Antigen: ITPKA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ITPKA
• Gene Alias: EC 2.7.1.127, inositol 1,4,5-triphosphate 3-kinase, inositol 1,4,5-trisphosphate 3-kinase A, inositol 145-triphosphate 3-kinase, inositol-trisphosphate 3-kinase A, insP 3-kinase A, IP3 3 kinase A, IP3 3-kinase A, IP3-3KA, IP3K A, IP3KA, IP3-kinase A, ITPKA
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 228550, 81677
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot
• Concentration: 1.78 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
• Gene Accession No.: P17105, Q8R071
• Gene Symbols: ITPKA
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse IP3KA.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG