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Invitrogen™ ITPKB Polyclonal Antibody
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Catalog No. PIPA536964
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PIPA536964 100 μL
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Catalog No. PIPA536964 Supplier Invitrogen™ Supplier No. PA536964
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 74 and 120 kDa. Purity is >95% by SDS-PAGE.

Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) regulates the level of calcium within the cell by releasing calcium from intracellular stores. Ins(1,4,5)P3 is phosphorylated by inositol 1,4,5-trisphosphate 3-kinase (IP3K) to form inositol 1,3,4,5-tetrakisphosphate (Ins(1,4,5)P4), which is is thought to regulate the influx of calcium across the plasma membrane. IP3K exists as three isoforms, IP3KA, B, and C. IP3KA, the most highly characterized isoform, is expressed in rat brain and testis. IP3KB is expressed in various rat tissues such as lung, thymus, testis, brain, and heart. IP3K activity is stimulated in the presence of calmodulin via phosphorylation by cAMP-dependent protein kinase, protein kinase C, or calcium/calmodulin dependent protein kinase II and, subsequently, mediates the inositol phosphate signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITPKB
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ITPKB
Gene Accession No. P27987, P42335
Gene Alias 1110033J02Rik; E130307H12Rik; Inositol 1,4,5-trisphosphate 3-kinase B; inositol-trisphosphate 3-kinase B; insP 3-kinase B; IP3 3-kinase B; IP3-3KB; IP3K; IP3K B; IP3KB; IP3K-B; Itpkb; PIG37; proliferation-inducing protein 37
Gene Symbols ITPKB
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 205-250 of human ITPKB.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 320404, 3707, 54260
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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