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Invitrogen™ IVNS1ABP Polyclonal Antibody
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Catalog No. PIPA551926
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PIPA551926 100 μL
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Catalog No. PIPA551926 Supplier Invitrogen™ Supplier No. PA551926
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QDELIEKPMS PMQYARSGLG TAEMNGKLIA AGGYNREECL RTVECYNPHT DHWSFLAPMR TPRARFQMAV LMGQLYVVGG SNGHSDDLSC GEMYDSNIDD WIPVPELRTN RCNAGVCALN GKLYIVGGSD Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

IVNS1ABP is a protein coding gene involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro).; (Microbial infection) involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IVNS1ABP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IVNS1ABP
Gene Accession No. Q9Y6Y0
Gene Alias 1190004M08Rik; 1700126I16Rik; AA960440; ARA3; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3; FLARA3; HSPC068; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; Influenza virus NS1A-binding protein homolog; Ivns1abp; kelch family protein Nd1; kelch family protein Nd1-L; kelch-like family member 39; Kelch-like protein 39; KIAA0850; KLHL39; mKIAA0850; NCX downstream gene 1; ND1; Nd1L; Nd1-L; ND1-L2; Nd1S; Nd1-S; NS1; NS-1; NS1-binding protein; NS1-binding protein homolog; Ns1bp; NS1-BP
Gene Symbols IVNS1ABP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IVNS1ABP. Recombinant protein control fragment (Product #RP-102250).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10625
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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