Tocris Bioscience IWP L6
Potent PORCN inhibitor
Manufacturer: Tocris Bioscience 4992/10
DescriptionPotent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys.
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