IWS1 Polyclonal Antibody, Bethyl Laboratories

Catalog No.
50-156-8180	20 μL; Unconjugated

Catalog No. 50-156-8180 Supplier Bethyl Laboratories, Inc Supplier No. A304609AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Specifications

• Antigen: IWS1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: IWS1
• Gene Accession No.: Q8C1D8, Q96ST2
• Gene Alias: IWS1-like protein, interacts with Spt6, protein IWS1 homolog
• Gene Symbols: IWS1
• Host Species: Rabbit
• Immunogen: Between 1 and 50
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55677, 73473
• Target Species: Human, Mouse
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG