Invitrogen™ IYD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563757

Catalog No. PIPA563757

Description

Immunogen sequence: ADRSMEKKKG EPRTRAEARP WVDEDLKDSS DLHQAEEDAD EWQESEENVE HIPFSHNHYP EK Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 65%.

This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: IYD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IYD
• Gene Alias: C6orf71; DEHAL1; dJ422F24.1; iodotyrosine dehalogenase 1; iodotyrosine dehalogenase 1; iodotyrosine deiodinase 1; iodotyrosine deiodinase; iodotyrosine deiodinase 1; IYD; IYD-1; RGD1309288; TDH4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 389434
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6PHW0
• Gene Symbols: IYD
• Immunogen: Recombinant protein corresponding to Human IYD. Recombinant protein control fragment (Product #RP-101082).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG