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  5. Tocris Bioscience™ J 147

Tocris Bioscience™ J 147
GREENER_CHOICE

Catalog No. 508150R
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels

J 147 is a potent neuroprotective and neurotrophic compound. Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM). Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo. Enhances memory in wild type rats. Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively. Orally active.

Specifications

Quantity 50 mg
Product Type J 147
Purity >99%
Molecular Weight (g/mol) 350.33
Inhibitors J 147

For Research Use Only

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