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Invitrogen™ J Chain Monoclonal Antibody (SP105)
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Catalog No. PIMA516419
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500 μL
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Catalog No. Quantity
PIMA516419 500 μL
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Catalog No. PIMA516419 Supplier Invitrogen™ Supplier No. MA516419
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Description

Rabbit Monoclonal Antibody

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is tonsil tissue.

J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
TRUSTED_SUSTAINABILITY

Specifications

Antigen J Chain
Applications Flow Cytometry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SP105
Concentration Conc. not determined
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene JCHAIN
Gene Accession No. P01591
Gene Alias 9530090F24Rik; AI323815; IGCJ; Igj; IgJ chain; immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin joining chain; immunoglobulin joining gene (not J region); J chain; Jch; JCHAIN; Joining chain of multimeric IgA and IgM
Gene Symbols JCHAIN
Host Species Rabbit
Immunogen Synthetic peptide near the internal region of human J-chain.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3512
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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