Invitrogen™ J Chain Recombinant Rabbit Monoclonal Antibody (PD00-89)

Catalog No.	Quantity
FEMA550730	100 μL

Catalog No. FEMA550730 Supplier Invitrogen™ Supplier No. MA550730

Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Human tonsil tissue, Daudi. Predicted band size: 18 kDa Subcellular Location: Secreted.

J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.

Specifications

• Antigen: J Chain
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Classification: Recombinant Monoclonal
• Clone: PD00-89
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: JCHAIN
• Gene Accession No.: P01591
• Gene Alias: 9530090F24Rik; AI323815; IGCJ; Igj; IgJ chain; immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin joining chain; immunoglobulin joining gene (not J region); J chain; Jch; JCHAIN; Joining chain of multimeric IgA and IgM
• Gene Symbols: JCHAIN
• Host Species: Rabbit
• Immunogen: Synthetic peptide within Human J Chain aa 50-150 (internal sequence).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3512
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG