Invitrogen™ JAB1 Monoclonal Antibody (2A10.8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA123244

Catalog No. PIMA123244

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, MCF-7, MDA-MB-231, Rat liver.

JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the 'Signalosome', which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.

Specifications

• Antigen: JAB1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O35864, Q92905
• Gene Symbols: Cops5
• Immunogen: The full-length mouse JAB-1 gene expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Drosophila
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 2A10.8
• Conjugate: Unconjugated
• Gene: Cops5
• Gene Alias: 38 kDa Mov34 homolog; AI303502; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana); COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; COP9 signalosome subunit 5; Cops5; CSN5; JAB1; Jun activation domain-binding protein 1; Jun coactivator; Kic2; Kip1 C-terminus-interacting protein 2; MGC3149; Mov34; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10987, 26754, 312916
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid