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Invitrogen™ JAB1 Polyclonal Antibody
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Catalog No. PIPA529872
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100 μL
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PIPA529872 100 μL
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Catalog No. PIPA529872 Supplier Invitrogen™ Supplier No. PA529872
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (99%), Xenopus laevis (99%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the 'Signalosome', which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JAB1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Cops5
Gene Accession No. O35864, Q92905
Gene Alias 38 kDa Mov34 homolog; AI303502; COP9 (constitutive photomorphogenic) homolog, subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana); COP9 complex S5; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; COP9 signalosome subunit 5; Cops5; CSN5; JAB1; Jun activation domain-binding protein 1; Jun coactivator; Kic2; Kip1 C-terminus-interacting protein 2; MGC3149; Mov34; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
Gene Symbols Cops5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Jab1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10987, 26754
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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