JAG1 Monoclonal Antibody (OTI3A10), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-1855	100 μL

Catalog No. 50-168-1855 Supplier OriGene Supplier No. TA807944

Description

Mouse Monoclonal Antibody

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Specifications

• Antigen: JAG1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI3A10
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: JAG1
• Gene Accession No.: P78504
• Gene Alias: AGS, AGS1, AHD, AWS, CD339, HJ1, JAGL1
• Gene Symbols: JAG1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 523-759 of human JAG1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 182
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a