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Invitrogen™ Jagged1 Monoclonal Antibody (S.522.2)
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Catalog No. PIMA515018
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100 μL
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PIMA515018 100 μL
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Catalog No. PIMA515018 Supplier Invitrogen™ Supplier No. MA515018
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with Jagged2.

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Jagged1
Applications Western Blot
Classification Monoclonal
Clone S.522.2
Concentration 246 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene JAG1
Gene Accession No. P78504
Gene Alias ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1
Gene Symbols JAG1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding Gly867 (extracellular region) of human Jagged1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 182
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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