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Invitrogen™ Jagged1 Polyclonal Antibody
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Catalog No. PIPA546970
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100 μg
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Catalog No. Quantity
PIPA546970 100 μg
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Catalog No. PIPA546970 Supplier Invitrogen™ Supplier No. PA546970
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 20% cross-reactivity with recombinant rat Jagged 1 is observed and less than 1% cross-reactivity with recombinant human Jagged 2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Jagged1
Applications Immunohistochemistry (Paraffin), Neutralization, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene JAG1
Gene Accession No. P78504
Gene Alias ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1
Gene Symbols JAG1
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Jagged 1 Ser32-Asp296.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 182
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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