Invitrogen™ Jagged1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582765

Catalog No. PIPA582765

Description

Immunogen sequence: LRKRRKPGSH THSASEDNTT NNVREQLNQI KNPIEKHGAN TVPIKDYENK NSKMSKIRTH NSEVEEDDMD KHQQKARFAK QPAYTLVDRE EKPPNGTPTK HPNWTNKQDN RDLESAQSLN RMEYI.

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Specifications

• Antigen: Jagged1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JAG1
• Gene Alias: ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 182
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P78504
• Gene Symbols: JAG1
• Immunogen: Recombinant protein corresponding to Human JAG1. Recombinant protein control fragment (Product #RP-93722).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov