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Invitrogen™ JAKMIP1 Polyclonal Antibody
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Catalog No. PIPA5100273
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PIPA5100273 100 μL
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Catalog No. PIPA5100273 Supplier Invitrogen™ Supplier No. PA5100273
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total JAKMIP1.

JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JAKMIP1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene JAKMIP1
Gene Accession No. Q8BVL9, Q96N16
Gene Alias 5830437M04Rik; C330021K24Rik; FLJ31564; GABA-B receptor-binding protein; Gababrbp; gamma-aminobutyric acid (GABA-B) receptor binding protein; Jak and microtubule interacting protein 1; Jakmip1; JAMIP1; janus kinase and microtubule interacting protein 1; janus kinase and microtubule-interacting protein 1; MARLIN1; Marlin-1; Multiple alpha helices and RNA-linker protein 1; multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein
Gene Symbols JAKMIP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human JAKMIP1(Accession Q96N16), corresponding to amino acid residues K434-A484.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 152789, 76071
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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