Invitrogen™ JAKMIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560756

Catalog No. PIPA560756

Description

Immunogen sequence: LVEKNKRMNK KNEDLLQSIQ RMEEKIKNLT RENVEMKEKL SAQASLKRHT SLNDLSLTRD EQEIEFLRLQ VLEQQHVIDD LSL Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.

JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.

Specifications

• Antigen: JAKMIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JAKMIP1
• Gene Alias: 5830437M04Rik; C330021K24Rik; FLJ31564; GABA-B receptor-binding protein; Gababrbp; gamma-aminobutyric acid (GABA-B) receptor binding protein; Jak and microtubule interacting protein 1; Jakmip1; JAMIP1; janus kinase and microtubule interacting protein 1; janus kinase and microtubule-interacting protein 1; MARLIN1; Marlin-1; Multiple alpha helices and RNA-linker protein 1; multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 152789
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96N16
• Gene Symbols: JAKMIP1
• Immunogen: Recombinant protein corresponding to Human JAKMIP1. Recombinant protein control fragment (Product #RP-96694).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG