Invitrogen™ JAKMIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116582

Catalog No. PIPA5116582

Description

Positive Samples: A-549, 293T, HepG2, HeLa, K-562, Jurkat, Mouse brain, Rat brain Immunogen sequence: EKQEAENHRL QQELQDARDQ NELLEFRNLE LEERERRSPP FNLQIHPFSD GVSALQIYCM KEGVKDVNIP DLIKQLDILG DNGNLRNEEQ VAIIQASTVL SLAEKWIQQI EGAEAALHQK MMELESDMEQ FCKIKGYLEE ELDYRKQALD QAYMRIQELE ATLYNALQQE TVIKFGELLS EKQQEELRTA VEKLRRQMLR KSREYDCQIL QERMELLQQA HQRIRDLEDK TDIQKRQIKD LEEKSNRKHG.

JAKMIP2 (janus kinase and microtubule-interacting protein 2), also known as NECC1 (neuroendocrine long coiled-coil protein 1), CTCL tumor antigen HD-CL-04, JAMIP2 or KIAA0555, is a 810 amino acid protein belonging to the JAKMIP family. Localizing to the Golgi apparatus, JAKMIP2 is high expressed in brain, with moderate levels of expression found in thymus, spleen and lung. Existing as three alternatively spliced isoforms, the gene encoding JAKMIP2 maps to human chromosome 5q32 and mouse chromosome 18 B3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Specifications

• Antigen: JAKMIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Jakmip2
• Gene Alias: 6430702L21Rik; AI850334; CTCL tumor antigen HD-CL-04; D930046L20Rik; Jak and microtubule interacting protein 2; JAKMIP2; JAMIP2; janus kinase and microtubule interacting protein 2; janus kinase and microtubule-interacting protein 2; KIAA0555; NECC1; Neuroendocrine long coiled-coil protein 1; RGD1559742
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 307479, 76217, 9832
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.90 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q96AA8
• Gene Symbols: Jakmip2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 561-810 of human JAKMIP2 (NP_0556052).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG