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JAM1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985557
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50-198-5557 100 μL
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Catalog No. 50-198-5557 Supplier Bioss Supplier No. BS3651R
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Description

Rabbit Polyclonal Antibody

CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.

Specifications

Antigen JAM1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene F11r
Gene Accession No. Q9Y624
Gene Alias 9130004G24; AA638916; BV11 antigen; CD321; ESTM33; F11 R; F11 receptor; F11 receptor/F11R; F11r; JAM; Jam1; JAM-1; JAMA; JAM-A; Jcam; Jcam1; junction cell adhesion molecule A; junction cell adhesion molecule1; Junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; Ly106; PAM-1; Platelet adhesion molecule 1; Platelet F11 receptor; UNQ264/PRO301
Gene Symbols F11r
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50848
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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