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JARID1B Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501571979
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50-157-1979 100 μL
50-157-1980 10 μL
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Catalog No. 50-157-1979 Supplier Bethyl Laboratories, Inc Supplier No. IHC00370
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Dog, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Smal

KDM5B is a histone demethylase that demethylates ′Lys-4′ of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 ′Lys-9′ or H3 ′Lys-27′. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 ′Lys-4′. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.

Specifications

Antigen JARID1B
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene KDM5B
Gene Accession No. Q9UGL1
Gene Alias RBBP2H1A, PLU1, PLU-1, CT31, lysine K-specific demethylase 5B, JARID1B, PUT1
Gene Symbols KDM5B
Host Species Rabbit
Immunogen Between 1494 and 1544
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10765
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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